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The peptides include BPC-157, KPV, TB-500 and MOTs-C, each with intended medical uses for ulcerative colitis

Molecular dynamics (MD) simulations, mass spectrometry and E194A site-directed mutagenesis revealed that PARP1-mediated ribosylation of PXR E194 enhanced CYP3A4 transcription, ultimately leading to excessive NAPQI production

PMID 18606874

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